Crossed Claisen and Dieckmann

The existing Claisen page is the self-condensation. These are the two variants students need for synthesis.

• Crossed Claisen: one ester has no α hydrogen, so only one enolate can form. Predict the β-keto ester.
• What goes wrong if both esters are enolizable.
• Dieckmann condensation: an intramolecular Claisen of a diester, giving a cyclic β-keto ester.
• Ring size: five- and six-membered rings form readily.
• Retrosynthesis: seeing a cyclic β-keto ester and disconnecting it to a diester.