The Cahn-Ingold-Prelog (CIP) system is used to determine absolute configuration of a chiral center. This is crucial for distinguishing between different stereoisomers. The rules for assigning priorities are as follows:
Atomic Number Priority:
Substituent Chain Priority:
Double and Triple Bonds Expansion:
Once the priorities are assigned, the configuration around the chiral center can be determined using these steps:
Position the Lowest Priority Group:
Analyze the Arrangement:
These CIP rules and configuration notations are essential for accurately describing the 3D arrangement of atoms around chiral centers and for understanding the stereochemistry of molecules.